Its main function is to transport long-chain fatty acids into the cells, where they can be metabolised to produce energy
Common adverse effects of GLP-1 receptor agonists include: Gastrointestinal symptoms (nausea, vomiting, diarrhoea, constipation) Injection site reactions Headache Fatigue Dizziness Important safety considerations include: Risk of hypoglycaemia when used with insulin or sulfonylureas (dose reduction of these agents may be needed) Potential worsening of diabetic retinopathy with semaglutide in patients with pre-existing retinopathy [18] Risk of dehydration and acute kidney injury from persistent vomiting or diarrhoea Pancreatitis, gallbladder disease, and potential thyroid C-cell tumours (observed in rodent studies, though human relevance remains uncertain) [19] [20] Patients should be counselled about persistent severe abdominal pain as a potential warning sign of pancreatitis requiring immediate medical attention
A: Most people feel only a small prick similar to a blood draw when the IV is placed
They also help manage blood sugar levels and prevent insulin spikes, which is crucial for those on GLP-1
They also reduce glucagon release
A: Subcutaneous injection into abdominal adipose tissue (12 inches lateral to the navel) provides consistent absorption kinetics