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Knowing that semaglutide improves liver health independently of weight loss could influence prescribing decisions

Simultaneously, it suppresses glucagon secretion, slows gastric emptying, and reduces appetite, contributing to weight loss in many patients

Severe side effects of the medication are: Severe gastrointestinal problems Low blood sugar levels (hypoglycemia) Changes in vision due to diabetic retinopathy pancreatitis Gallbladder problems Hypoglycemia Allergic reaction to the medication Severe stomach pain Risk of aspiration during sedation or anesthesia Mood and behavioural changes Suicidal ideation Limitations Semaglutide is contraindicated for patients with a history or family history of thyroid cell tumors (MTC) and endocrine cancers (MEN 2 syndrome) because the medication increases the risk of these tumors in rodent studies

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One proposed advantage of AOD-9604 is that it minimally impacts insulin levels compared to full growth hormone