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Treatment typically begins at 0.25 mg weekly for at least four weeks, then increases through 0.5 mg, 1 mg, and 1.7 mg (each for at least four weeks), reaching the maintenance dose of 2.4 mg by week 17

For researchers who have experience switching from tirzepatide to retatrutide or other peptide transitions , similar principles apply

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Reactions included nausea, vomiting, chills, low blood pressure, difficulty breathing , and in some cases, possible bloodstream infection

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