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Study Selection The trials we included met the following criteria: (1) RCTs that compared GLP-1 receptor agonist with a placebo or active control (other antidiabetic drugs or insulin), (2) patients with type 2 diabetes, type 1 diabetes, prediabetes, overweight or obesity, (3) with durations of at least 24 weeks, and (4) reported the occurrence of at least one case of various thyroid disorders as adverse events

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Many patients see meaningful A1C improvement here

Lawsuits allege that the drug manufacturers failed to warn about the heightened risk of pancreatitis, despite evidence from clinical trial data and adverse event reports