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4.3 Protein-based NPs Protein-based NPs (PNPs) have emerged as a transformative strategy to counteract melanomas immunosuppressive TME, addressing key challenges such as immune evasion, defective antigen presentation, and impaired cytotoxic T cell activity ( Table 3 )

These constructs are related but not interchangeable and are addressed at different mechanistic levels throughout the manuscript

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There is little research regarding the selection, implementation, and treatment course for KMT use as adjunctive or sole treatment in individual psychiatric conditions

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It is a large and complex ecosystem of components, each with its own mission, technology priorities, and funding mechanisms