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Meilandt WJ, Yu GQ, Chin J et al (2008) Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimers disease

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88% were male

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References: Raun K, Hansen BS, Johansen NL, Thgersen H, Madsen K, Ankersen M, Andersen PH

We believe maintaining the glutathione-to-iron ratio is very important, because if you have too little glutathione, then iron becomes very reactive, and if you have too much glutathione, the iron will not be usable. Their experiments determined that SLC25A39 carries a unique iron signature on its surface as part of the glutathione sensing mechanism