Genetic disruption of the Gipr in Apoe(/) mice promotes atherosclerosis
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Reduce if gastrointestinal symptoms remain severe after six or more weeks at a given dose level, if significant dehydration results from persistent vomiting or diarrhea, if heart rate increases beyond 15 beats per minute above baseline, or if the side effect burden is causing protocol abandonment
Non-Diabetic PAD Patients on GLP-1RAs Show Reduced Risk of Serious Cardiovascular Outcomes Compared to Those Without GLP-1RAs PAD is a condition where the peripheral arteries that carry blood away from the heart to other parts of the body become narrowed or blocked, reducing blood flow to the limbs, often in the legs
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Holtmaat AJGD, Trachtenberg JT, Wilbrecht L, Shepherd GM, Zhang X, Knott GW, Svoboda K (2005) Transient and persistent dendritic spines in the neocortex in vivo