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Investigated in rodent and non-human primate models of diet-induced obesity, hepatic steatosis and glycaemic dysregulation
Pharmacologically, it is activated by the endogenous incretin hormone GLP-1 as well as by therapeutic agonists such as exenatide, liraglutide, semaglutide, and dulaglutide, which are widely used to treat type 2 diabetes and obesity
Take care to store semaglutide properly, and dont use improperly stored semaglutide (such as Ozempic pens left in the car)
Cureus 14, e27132
In the secondary prevention population, the ICERs were AU$8878 for SGLT2is and AU$79,742 for GLP-1 RAs
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