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Rebound Hypertension Crisis: Abrupt discontinuation of clonidine can trigger severe rebound hypertension, tachycardia, headache, and agitation within 24 to 36 hours (Cao et al., 2022

A single intragastric alcohol dose caused gastric lesions, brain swelling, intracranial hypertension, liver and kidney damage, lung injury, and severe thrombosis

Some studies suggest potential roles in angiogenesis, collagen-related repair processes, inflammatory signaling, and protection of different tissue types

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attributed the toxic effect of MTX to mitochondrial dysfunction and oxidative stress through interaction with molecular oxygen, triggering a series of reactions that release reactive oxygen and nitrogen species

Liu M, Hu Z, Qi L et al (2013) Scanning of novel cancer/testis proteins by human testis proteomic analysis