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However, when the amount of ROS becomes greater than the bodys normal cleanup mechanisms can easily handle, the result is increased oxidative stress on the body

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Unlike the previously described pathways, FIN56 stimulates ferroptosis by consuming GPX4 proteins and blocking lipophilic antioxidants, such as coenzyme Q10 (Shimada et al., 2016b)

In Experiment 2, due to limited sample size, data from both sexes were pooled and analyzed using oneway ANOVAs for cumulative curve and acute administration measures

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