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In a combined analysis of three trials with 1,119 participants, individuals with PAM variants responded less effectively to GLP-1 drugs and were less likely to reach target HbA1c levels, a measure of long-term blood sugar control

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GLP-1 RAs showed a trend toward favorable neurological outcomes, including improved cognitive function in individuals with AD/MCI, reduced dementia risk in individuals with T2DM, and improvements in Parkinsons disease scores

Who Can Benefit from Semaglutide Treatment

Updated 2023 May 23