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Your GP may arrange investigations based on clinical findings, potentially including: Blood tests : To assess electrolytes, renal function, and glucose control Chest X-ray : If diaphragmatic irritation or thoracic pathology is suspected Upper gastrointestinal endoscopy : If reflux or structural abnormalities are suspected Further imaging : Such as CT scans, if clinically indicated Pharmacological options for persistent hiccups are generally prescribed off-label (not licensed specifically for hiccups) and should be initiated and monitored by a clinician: Metoclopramide : A prokinetic agent that enhances gastric emptying