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non-hormonal mechanism means it doesnt rely on estrogen or testosterone manipulation
(PubMed) Negida A, Menshawy A, El Ashal G, et al
It works as a glucagon-like peptide 1 (GLP 1) receptor agonist, which means it boosts insulin secretion in response to glucose and reduces the amount of ghrelin produced by the stomach
An emerging area in GPCR biology is identifying partner or accessory proteins and understanding how GPCR interacting proteins help control signaling
Neuroreport 20(13):11611166 Hamilton A, Patterson S, Porter D, Gault VA, Holscher C (2011) Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain
At 1 mg weekly, participants lost modest amounts
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