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They activate GLP-1 receptors in the pancreas, the gut, and critically, the brain

Some, like AOD 9604 peptide , target fat metabolism directly and may complement GLP-1 therapy for people who plateau

The change in the imputation method did not make a significant impact on the premium or contribution estimates

, The reason for this may include improved function of muscle mitochondria, a part of the muscle cell that provides the energy the muscle cell needs to function

Sources: Fierce Biotech: What are your thoughts on the future of multi-receptor agonists in obesity

Popov LD (2020) Mitochondrial biogenesis: an update