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As such, insurers may not capture the full economic benefit of improved mortality and morbidity

Additionally, hormonal changes occur during weight loss, including alterations in leptin, ghrelin, and other appetite-regulating hormones, which may increase hunger signals and reduce satiety over time

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However, things may be changing in the research world

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Studies in mice have shown that GLP-1s also reduce "nicotine-induced increases in dopamine release" in a specific brain area, "a common mechanism underlying the rewarding effects of addictive drugs," the researchers explained