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The bowel wall can have weak spots in the wall of the large intestine
Other conditions associated with debilitating pain in which fibroblasts contribute include chronic pain, in which fibroblasts are responsible for releasing proalgesic mediators and sustaining inflammatory responses (86), or carpal tunnel syndrome, a peripheral neuropathy characterised by fibrosis occurring in the subsynovial connective tissue in the carpal tunnel, with fibroblast hyperplasia, disorganised collagen deposition and increased expression of TGF-1 pathway components (87)
Normally, your stomach empties its contents pretty quickly after you eat
The unprecedented surge in demand meant that all parts of the supply chain were stretched to the limit, to the point where even auto-injector pens were in short supply
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