Finally, low glutamine in the core region of solid tumors led to histone hypermethylation due to decreased -ketoglutarate level, resulting in cell dedifferentiation and therapeutic resistance in melanoma cells [64]
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The right temporal muscle was dissected, the temporal bone dried, and a laser Doppler flow (LDF) probe was attached to the temporal bone to monitor regional cerebral blood flow (rCBF) during the procedure
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Yang L, Wei Y, Sun Y, Shi W, Yang J, Zhu L, et al