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Again, this is where estradiol also exerts a number of direct effects on appetite, thus raising the possibility of estradiol-insulin interactions to alter food intake
Criteria typically include a documented diagnosis of T2DM (ICD-10 E11.x), prior trial or contraindication to metformin, and HbA1c documentation within the last 12 months
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Wilding, John P.H., et al
Affected areas of the face include the cheeks, upper lip, and forehead
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