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Like any medication, GLP-1s come with known side effects that can affect both men and women, including nausea, constipation, diarrhea, and fatigue

The preliminary cardiovascular safety data for DPP-4 inhibitors are promising, and, if the results of long-term cardiovascular studies demonstrate reductions in hard cardiovascular end points, then this may consolidate the position of the DPP-4 inhibitors as the second-line choice for combination with metformin

Igwebuike UM, Ochiogu IS, Ihedinihu BC, Ikokide JE, Idika IK

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Overbaugh JM, Fall R (1985) Characterization of a selenium-independent glutathione peroxidase from Euglena gracilis

[Abstract] Angew Chem Int Ed Engl