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Although its often spoken about as one thing, its consequences look different depending on the organ system involved: Metabolic organs (liver, adipose tissue, pancreas): Chronic inflammation here is associated with insulin resistance, higher glucose, and fatty liver disease. Blood vessels / cardiometabolic system: Inflammation contributes to long-term cardiovascular risk, and GLP-1 therapies improve several cardiometabolic risk factors, including blood pressure. Kidneys: Metabolic stress accelerates kidney damage and albuminuria

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