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The production of free radicals alters the working condition of macromolecules such as proteins, lipids, and DNA, impairing an individuals ability to maintain homeostasis (Pomatto and Davies, 2018)
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Furthermore, engineered approaches, such as CAR-macrophages targeting HER2 and CD47, have demonstrated efficacy in promoting phagocytosis of ovarian cancer cells and activating adaptive immunity (81)
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That systemic reach is actually an advantage if you're dealing with more than one problem at once
Reid, M., Badaloo, A., Forrester, T
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