Building on the success of tirzepatidethe first approved dual GLP-1/GIP co-agonistother dual agonists, including those targeting both GLP-1 and GCG receptors, are in an advanced stage of development
Funduscopy revealed pronounced optic disc edema in OD, accompanied by peripapillary intraretinal fluid and buried ODD detected on OCT
The long half life gives you some flexibility, so an occasional small shift is not a problem
And so they were drinking quite heavily, but they were not trying to stop or cut down on their drinking
Escalation: The dose is then gradually increased, typically every four weeks, to 0.5 mg, then 1 mg, 1.7 mg (for Wegovy), and finally to a maintenance dose of up to 2 mg (for Ozempic) or 2.4 mg (for Wegovy) once weekly
Delayed dose escalation: Remaining at an approved dose longer because of side effects, tolerance or other clinical considerations