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Primary action: inhibition of the NNMT enzyme

Similarly, tirzepatide, a dual GLP-1/GIP receptor agonist, demonstrated impressive results in the SYNERGY-NASH trial, with a high percentage (74%) of participants achieving an absence of NASH and no worsening of fibrosis

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Clinical Trials A small, early-phase randomized clinical trial at the University of North Carolina at Chapel Hill School of Medicine found that low-dose semaglutide significantly reduced alcohol cravings and total consumption in adults over 9 weeks

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