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Cellular effects duration vs plasma half-life Critical distinction: Plasma half-life duration of effects GHK-Cu clears blood in hours But cellular effects last days How GHK-Cu works: Peptide binds to cell surface receptors Triggers intracellular signaling cascades Activates gene expression changes Initiates collagen synthesis, wound healing, etc

Answer: Because Dihexa is investigational, its long-term safety profile in humans is not fully established

This keeps the work aligned with regulatory guidance while still allowing for detailed exploration of how the peptide behaves in various models

Nothing in this guide is overstated

The Category 1 status is provisional pending PCAC review before end of February 2027

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