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Among organelles, mitochondria play a central role in ROS generation (Fig
Proteomics analysis of therapeutic performance of D-CuP To elucidate the regulatory mechanisms of D-CuP, we conducted a quantitative proteomics analysis on murine L929 fibrosarcoma cells before and after treatment under nutrient stress (Fig
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Yet as our understanding of cellular signaling and regulatory pathways has developed, so has our insight into the involvement of GSH homeostasis in many other key processes, including the regulation of cellular proliferation and apoptosis and the post-transcriptional modification of proteins through S-glutathionylation, as well as the importance of GSH in the detoxification of hydroperoxides and diverse xenobiotic compounds
