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10.1073/pnas.78.5.2777 Proc Natl Acad Sci USA
But it is precisely the kind of science that Calico Life SciencesAlphabets longevity research subsidiaryand Insilico Medicine are watching closely, because it suggests the mitochondrial genome harbors a pharmacopoeia of untapped bioactive molecules
In these antioxidant reactions, glutathione is oxidized to form the oxidized disulfide form, GSSG which is then, in turn, reduced back to glutathione using NADPH.[ref] Mitochondria are essential for the production of ATP for energy storage in cells
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Sallach, G
To test whether the observed reduction in PhoA activity is dependent on glutathione levels in the periplasm, we also measured PhoA activity in a cydD mutant
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