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This discrepancy may be attributable to the slowing of gastric emptying induced by metformin [8], which would blunt the postprandial insulin response

Does this mean the medication isnt working

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Flvio conducts a full medical evaluation before prescribing and monitors you throughout this is the standard of care, not a shortcut

Brief discomfort is common with subcutaneous injections

Additionally, GLP-1R, expressed in human kidneys proximal tubular cells, the renal vasculature, the preglomerular vascular smooth muscle cells, and juxtaglomerular cells could directly contribute to these functions