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For example, in myocardial tissues, H 2 treatment scavenged ROS by upregulating the heme oxygenase-1 (HO-1, known as heat shock protein 32) to protect sepsis-related multiple organ injury in HO-1/Nrf2 dependent manner (Zhang et al., 2020)

Various interactions between antioxidants and enzymes have been observed in hepatic diseases

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