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Conclusion: ATZ/BEV therapy seems to benefit mainly BCLC-C patients who migrate from earlier stages after curative LR or RFA compared to patients initially presented in the advanced stage, irrespective of liver disease severity and these patients exhibit better disease response rates

When [Ca 2+ ] i changed within 5 min after addition of agents and their amplitudes were at least twice larger than the fluctuations of the baseline, they were considered responses

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