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By incorporating estrous monitoring into current pre-clinical biomedical research, experimenters can assess differential effects of drugs and doses across estrous phases, which will be critical for understanding how drugs interact with endogenous fluctuations in hormonal state 72
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, 435 , 15-24, doi: Chen, M
9-13 In two of the trials, there was a significant association between the use of a synthetic GLP-1/GIP agonist and worse eye-related outcomes
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