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The goal of antimicrobial therapy is to prevent further infection, since neutropenia is associated with significantly increased susceptibility to pathogens (Friefeld 2011)

Upon binding to IL12R, the JAK2 was linked to IL12R2, and then STAT4 was phosphorylated, after which the dimerized STAT4 could be transferred to the nucleus to alter gene expression (48, 49)

They may test these separately before clearing them

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This matches the timeline where clinical studies show their most significant results