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Wilson JM, Nikooienejad A, Robins DA, Roell WC, Riesmeyer JS, Haupt A, Duffin KL, Taskinen MR, Ruotolo G
Consider two people who both lose 15 kilograms on a GLP-1 drug: Lost 15 kg but poorly 10 kg fat lost 5 kg muscle lost Metabolic rate has fallen Blood sugar control worsened Higher fall risk than before Weight regain likely as fat Lost 15 kg and well 14 kg fat lost 1 kg muscle lost (or neutral) Metabolic rate preserved Blood sugar control improved Strength maintained or increased Better long-term weight maintenance Both people lost the same amount of weight by the scale
Endocrine 62(3):535545
The glutathione system helps cells control peroxides and reactive electrophiles before they disrupt lipids, proteins, membranes or DNA
This inhibition presents itself with a reduction in hyperpigmentation and dark spots and overall skin lightening
GLP-1R (glucagon-like peptide-1 receptor) agonists are approved for the treatment of diabetes and obesity
