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Consistent with rapid generation of cAMP in response to this peptide, biotinylated GLP-1(2836) entered caSMCs with the strongest intracellular signals observed within 15 minutes (Supplemental Figure 5)
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Retrieved March 10, 2016
2.16 Peptide-membrane interaction assay by FRET T-REx-SNAP-GLP-1R cells were pre-treated 0.1 g/ml tetracycline to induce SNAP-GLP- 1R expression
This finding was further supported when pooled with further observational data 49,50 to a total of 210,521 people with T2DM up to 7.4 years on any GLP-1RA 40
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