Innovation : The current AOM pipeline comprises 157 clinical-stage assets, including 7 in phase 3, and spans over 60 mechanisms of action, while 43% of all AOM assets are oral therapies (see Figure 2)
Why Sublingual Semaglutide
Appetite and water retention naturally fluctuate through the month, and the scale can jump a few pounds around a period regardless of fat loss
Patients with a clinical history of chronic Gastroesophageal Reflux Disease (GERD) already possess a severely inflamed, hyper-reactive lower esophagus (esophagitis)
NEJM Nauck MA, Quast DR, Wefers J, Meier JJ
However, it's important to note that semaglutide delays gastric emptying, which may affect the absorption of some oral medicines, though this has not shown clinically relevant effects for most medications