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Review: Advances in GLP-1 receptor agonists delivery systems for obesity and diabetes A new review article published in the journal Acta Pharmaceutica Sinica B summarizes advancements in drug delivery systems for three main glucagon-like peptide-1 receptor agonists (GLP-1RAs), which are recommended for selected patients with obesity or type 2 diabetes, depending on indication, comorbidities, and treatment goals
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In PWA mice, treatment with GLP1/E caused a significant decrease in body weight (10%) and fat mass (50%), as well as a reduction in food intake and substantial improvement in glucose metabolism and insulin sensitivity, denoted by ITT and HOMA-IR, as well as serum glucose, insulin (Fig