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The effects remain an area of active research [2][19][20]

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They also concluded that gabapentinoids are associated with increased risk of drug poisoning and that close monitoring during treatment is necessary Concomitant use with opioid or benzodiazepines should be avoided, the authors added

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Regional prevalence rates are currently highest in the Middle East (32%) and South America (30%) and lowest in Africa (13%), but prevalence rates are even higher in specific subpopulations such as severely obese (90%) and patients with type 2 diabetes (76%) [1]