Research has demonstrated that, in comparative studies of anti-diabetic drugs, GLP-1RAs can significantly reduce the risk of liver decompensation and hepatocellular carcinoma in patients with type 2 diabetes [42]
Inhibition of glutathione synthesis in the newborn rat: a model for endogenously produced oxidative stress
Glutathione is the liver's major antioxidant, often depleted in fatty liver disease due to oxidative stress and inflammation
Pediatrics 2010;125:654-9
However, a third of high-dose patients experienced nausea while 24% experienced vomiting, compared with 10.4% and 3.5% respectively for the placebo group
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