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IGF-I/IGF-IR signaling in chondrogenesis Although the above global KO mice confirmed the importance of IGF-I/IGF-IR signaling in supporting skeletal development, they did not specify the action of IGF-I signaling in specific cell lineages in the bone or exclude the impact of other systemic derangements on the skeleton

Sattar N, Petrie MC, Zinman B, Januzzi JL Jr

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For those who have undergone cholecystectomy, additional consideration of digestive tolerance is prudent

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