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Every comparative claim in this article therefore carries a caveat: it is either an indirect comparison across trials with different populations, dosing schedules, and endpoints, or it is a mechanistic extrapolation from preclinical and Phase 2 data

Kurinami N, Takada M, Sugiyama S, et al

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Other symptoms of B12 deficiency, such as numbness and tingling in the hands and feet, are also common in people with diabetes and spinal stenosis

I tell patients to front-load protein at whichever meal their appetite is strongest, rather than spreading it thin across meals they may not finish