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The Researching Cardiovascular Events with a Weekly Incretin in Diabetes (REWIND) trial focused on adults aged 50 years with either established or newly diagnosed type 2 diabetes and additional cardiovascular risk factors, and this trial investigated subjects with HbA1c 9.5%, receiving up to two oral glucose-lowering drugs with or without basal insulin, and a body mass index of at least 23 kg/m 2

Fijak M, Pilatz A, Hedger MP, et al

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In contrast, lean individuals with stable glucose patterns may see limited value

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