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Eat a light meal beforehand to avoid nausea, and wear loose, comfortable clothing for ease
Furthermore, H&E staining showed that compared to the aorta of normal aging mice, the aorta of mice treated with FOXO4-DRI was thinner, and the PWV value was lower in the ultrasound detection results, which means that the mice treated with FOXO4-DRI had better vascular elasticity and better vascular function than normal aging mice (Figures 1D,E)
Adverse Effects Profile (Phase 2 Data) The Phase 2 NEJM 2023 trial reported the following adverse event profile
Konopleva M, Zeng Z, Samudio I, Bornmann W, Andreeff M
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