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Prescription weight loss medications: GLP-1 medications like Mounjaro have extensive clinical evidence showing 15-25% weight loss
Urva et al., 2022 (The Lancet): estudio fase 1 de farmacocintica en humanos sanos, confirmando vida media compatible con dosificacin semanal y perfil de tolerabilidad consistente con familia incretnica
Noticing changes in your appetite is trickier than tracking weight, but it is just as important
Patients should be educated to recognise and report warning signs promptly, including: Seizure warning signs : unusual sensations, confusion, loss of consciousness, or convulsive movements Cardiovascular symptoms : chest pain, palpitations, severe dizziness, or shortness of breath Psychiatric changes : worsening depression, anxiety, agitation, panic attacks, or thoughts of self-harm Severe gastrointestinal symptoms : persistent vomiting, severe abdominal pain (which may indicate pancreatitis), or signs of dehydration Hypoglycaemia symptoms (if diabetic): tremor, sweating, confusion, or rapid heartbeat Medication adherence and technique should be reviewed regularly
It should be kept at room temperature, away from direct sunlight or any other source of heat and moisture
An important study challenging the view that IRS1 is the critical biochemical site for IR
