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Starting with lower doses and gradually increasing can help minimize any gastrointestinal adjustment
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It is well established that triple-negative breast cancer (TNBC) is highly aggressive [22], with significantly higher rates of metastasis and recurrence compared to other breast cancer subtypes [23], especially in isceral and brain metastasis [24]
Gobburu, J.V.S., Agers, H., Jusko, W.J
The prior pharmacotherapy might have an influence on the levels of the measured individual baseline enzymatic activities and, hence, the patient clustering, but presently we can only note this fact to analyze larger groups in the future
Dominant evidence type Early pharmacology, animal-model work, small human PK/PD research, and limited clinical-development evidence
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