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The pharmacological treatment should therefore be tailored not only to achieve glycemic control but also to ensure cardiovascular protection and prevent the onset of overweight and obesity

Carnosine protects cardiac myocytes against lipid peroxidation products

J., Crdenas, M

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AMG 133 results in full agonism of human GLP-1R (EC 50 = 24.4 pM) and activated cynomolgus monkey and mouse GLP-1R (EC 50 of 5.7 and 123 pM, respectively)