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In some instances, however, the side effects may last much longer, including after discontinuing the drug

(2022) [59] comparing GLP-1RA plus SGLT2i combination therapy to GLP-1RA and SGLT2i monotherapies among 1,895 patients with T2DM enrolled in 8 RCTs, the addition of a GLP-1RA to SGLT2i treatment showed that drug discontinuation, diarrhea, injection-site-related events, nausea, vomiting and genital infections were more likely to occur in combination therapy

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Much of the available evidence comes from preclinical (animal/lab) studies and reviews, and BPC-157 is considered investigational in many settings

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Presented for research literature review only Luo Y et al