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Then, the heart was collected eight weeks after the administration of the treatment

Treatment continues only if HbA1c reduces by 11 mmol/mol and weight decreases by 3% at 6 months

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[6] A 2025 Scientific Reports meta-analysis of GLP-1 RAs in PCOS found similar patterns: GLP-1 agonists drive larger BMI and waist-circumference reductions than metformin, with a 33% reduction in testosterone reported in one pooled analysis