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Notably, when the GSH level decreases, impaired negative-feedback inhibition leads to the accumulation of -glutamylcysteine, which is converted to 5-oxoproline via the -glutamylcyclo-transferase pathway
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If your glutathione levels are lower than they should be, you could be at higher risk of experiencing several serious medical conditions
What is conspicuous is what is missing here: a dose-response gradient
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