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Naltrexone: Although commonly used to curb alcohol and opioid cravings, this medication can help with appetite control when combined with other drugs
News provided by Eli Lilly and Company May 21, 2026, 06:45 ET In TRIUMPH-1, participants on 12 mg retatrutide lost an average of 70.3 lbs (28.3%) over 80 weeks with 45.3% of participants achieving 30% weight loss, a level long associated with bariatric surgery Individuals with a baseline BMI 35 who participated in a study extension continued to lose weight, and achieved up to an average of 85.0 lbs (30.3%) weight loss at 104 weeks At the 4 mg dose, reached with only a single escalation step, participants lost an average of 47.2 lbs (19.0%) at 80 weeks with a lower observed discontinuation rate due to adverse events vs
[Abstract]2025 Jan 1;21(2):725-744
Craig CL, Marshall AL, Sjstrm M, Bauman AE, Booth ML, Ainsworth BE, et al
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