Currently the most serious vision risk from GLP-1 usage is NAION, which can cause total blindness
In order to make GLP-1 better used in the clinic, drug developers modified its structure and developed a series of GLP-1R agonists ( GLP-1, a 30- or 31-amino-acid-long peptide hormone, is a gastrointestinal peptide secreted by the intestinal tract that potentiates insulin release and reduces glucagons concentration in physiological conditions ( Scheme 1
It says the combination is typically not recommended for those with hepatic or renal impairment, uncontrolled hypertension, a history of pancreatitis, or medullary thyroid cancer risk
Synergistic Anticancer Effect of Melatonin and Ascorbyl Palmitate Nanoformulation: A Promising Combination for Cancer Therapy
PRP injections stimulate the skin's collagen synthesis, fostering improved elasticity and firmness for a naturally lifted appearance
Its impossible to know if this is due to reduced absorption or just the typical pill failure rate of 9% annually with typical use, but the theoretical risk is concerning enough that many doctors recommend alternative contraception