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However, prolonged or high-dose ketamine exposure induces a compensatory upregulation of NMDARs, increasing intracellular calcium ion influx and ROS production, ultimately leading to neuronal apoptosis (Liu et al., 2013)
PubMed Urva, S., Coskun, T., Loghin, C., Cui, X., Beebe, E., OFarrell, L., et al
Ever stumbled upon DSIP and wondered what magic it holds
D., Sousa, M
Hypoxia induces drug resistance in tumors Studies have indicated an increase in drug resistance in hypoxic tumors, with the activation of HIFs associated with tumor resistance and reduced survival rates [251]
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